2.25 米诺地尔........................................................................................................................298 2.26 氢醌、苯酚 ....................................................................................................................302 2.27 石棉................................................................................................................................308 2.28 维甲酸和异维甲酸 ........................................................................................................315 2.29 维生素 D2 和维生素 D3 .................................................................................................319 2.30 邻苯二甲酸二甲酯等 10 种组分 ..................................................................................322 2.31 邻苯二甲酸二丁酯等 8 种组分 ....................................................................................327 2.32 二氯甲烷等 15 种组分 ..................................................................................................332 2.33 乙醇等 37 种组分 ..........................................................................................................337 3 限用组分检验方法...................................................................................................................353 3.1 α-羟基酸............................................................................................................................353 3.2 二硫化硒..........................................................................................................................360 3.3 过氧化氢..........................................................................................................................363 3.4 间苯二酚..........................................................................................................................366 3.5 可溶性锌盐......................................................................................................................368 3.6 奎宁..................................................................................................................................370 3.7 硼酸和硼酸盐 ..................................................................................................................372 3.8 羟基喹啉..........................................................................................................................374 3.9 巯基乙酸..........................................................................................................................376 3.10 水杨酸............................................................................................................................383 3.11 酮麝香 ............................................................................................................................385 3.12 游离氢氧化物 ................................................................................................................387 3.13 总硒................................................................................................................................389 4 防腐剂检验方法.......................................................................................................................392 4.1 苯甲醇..............................................................................................................................392 4.2 苯甲酸及其钠盐 ..............................................................................................................399 4.3 苯氧异丙醇......................................................................................................................406 4.4 苯扎氯铵..........................................................................................................................409 4.5 劳拉氯铵、苄索氯铵和西他氯铵 ..................................................................................411 4.6 甲醛..................................................................................................................................413 4.7 甲基氯异噻唑啉酮等 12 种组分 ....................................................................................419 4.8 氯苯甘醚..........................................................................................................................423 4.9 三氯卡班..........................................................................................................................425 4.10 山梨酸和脱氢乙酸 ........................................................................................................427 4.11 水杨酸等 5 种组分 ........................................................................................................429 5 防晒剂检验方法..................................................................................................................432 5.1 苯基苯并咪唑磺酸等 15 种组分 ....................................................................................432 5.2 二苯酮-2...........................................................................................................................438 5.3 二氧化钛..........................................................................................................................441 5.4 二乙氨羟苯甲酰基苯甲酸己酯 ......................................................................................443 5.5 二乙基己基丁酰胺基三嗪酮 ..........................................................................................445 5.6 亚苄基樟脑磺酸 ..............................................................................................................447 5.7 氧化锌..............................................................................................................................450 6 着色剂检验方法.......................................................................................................................452 6.1 碱性橙 31 等 7 种组分 .....................................................................................................452 6.2 着色剂 CI 59040 等 10 种组分 ........................................................................................455 7 染发剂检验方法.......................................................................................................................461 7.1 对苯二胺等 8 种组分 ......................................................................................................461 7.2 对苯二胺等 32 种组分 ....................................................................................................464 第五章 微生物检验方法 .........................................................................................469 1 微生物检验方法总则...............................................................................................................469 2 菌落总数检验方法...................................................................................................................471 3 耐热大肠菌群检验方法...........................................................................................................474 4 铜绿假单胞菌检验方法...........................................................................................................477 5 金黄色葡萄球菌检验方法.......................................................................................................480 6 霉菌和酵母菌检验方法...........................................................................................................483 第六章 毒理学试验方法 .........................................................................................485 1 毒理学试验方法总则...............................................................................................................485 2 急性经口毒性试验...................................................................................................................486 3 急性经皮毒性试验...................................................................................................................488 4 皮肤刺激性/腐蚀性试验..........................................................................................................490 5 急性眼刺激性/腐蚀性试验......................................................................................................493 6 皮肤变态反应试验...................................................................................................................496 7 皮肤光毒性试验.......................................................................................................................500 8 鼠伤寒沙门氏菌/回复突变试验...........................................................................................503 9 体外哺乳动物细胞染色体畸变试验.......................................................................................510 10 体外哺乳动物细胞基因突变试验.........................................................................................513 11 哺乳动物骨髓细胞染色体畸变试验.....................................................................................516 12 体内哺乳动物细胞微核试验.................................................................................................519 13 睾丸生殖细胞染色体畸变试验.............................................................................................522 14 亚慢性经口毒性试验.............................................................................................................525 15 亚慢性经皮毒性试验.............................................................................................................528 16 致畸试验.................................................................................................................................532 17 慢性毒性/致癌性结合试验....................................................................................................535 第七章 人体安全性检验方法 .................................................................................540 1 人体安全性检验方法总则.......................................................................................................540 2 人体皮肤斑贴试验...................................................................................................................541IV 3 人体试用试验安全性评价.......................................................................................................543 第八章 人体功效评价检验方法 .............................................................................545 1 人体功效评价检验方法总则...................................................................................................545 2 防晒化妆品防晒指数(SPF 值)测定方法...........................................................................546 3 防晒化妆品防水性能测定方法...............................................................................................552 4 防晒化妆品长波紫外线防护指数(PFA 值)测定方法............................................................554 |